I was also not able to find "Database Configuration Wizard on 5.x" so what is the work-around if you want to configure a new database for use with SD 5 apart from the default configured during the insallation.
HI My SQL - MS. Every day at 4:00 run full back up of sd database, our db ~7GB. In This time we does have any activity, only sometime. So if you have too big db and on back up spend time too much, use full back up at weekends and in working days use "differental" backup when stored only changes , that quickest back up, but not have a long time to restore, because you must restore "full", then each day by day backup.
You basically used whatever your database tools for the backup and restore. For Oracle, use Oracle db backup & restore. For SQL server, use Sql Server backup and restore. There is no sd 5.1 utility to backup & restore and there is no need as the database own utility is best for this.